Gut microbiota DPP4-like enzymes are increased in type-2 diabetes and contribute to incretin inactivation.
Por:
Olivares M, Hernández-Calderón P, Cárdenas-Brito S, Liébana-García R, Sanz Y and Benítez-Páez A
Publicada:
3 jul 2024
Resumen:
The gut microbiota controls broad aspects of human metabolism and feeding behavior, but the basis for this control remains largely unclear. Given the key role of human dipeptidyl peptidase 4 (DPP4) in host metabolism, we investigate whether microbiota DPP4-like counterparts perform the same function.
Filiaciones:
Olivares M:
Institute of Agrochemistry and Food Technology, Microbiome, Nutrition and Health Research Unit, Spanish National Research Council, IATA-CSIC, 46980, Paterna-Valencia, Spain
Hernández-Calderón P:
Principe Felipe Research Center (CIPF), Host-Microbe Interactions in Metabolic Health Laboratory, 46012, Valencia, Spain
Cárdenas-Brito S:
Principe Felipe Research Center (CIPF), Host-Microbe Interactions in Metabolic Health Laboratory, 46012, Valencia, Spain
Liébana-García R:
Institute of Agrochemistry and Food Technology, Microbiome, Nutrition and Health Research Unit, Spanish National Research Council, IATA-CSIC, 46980, Paterna-Valencia, Spain
Sanz Y:
Institute of Agrochemistry and Food Technology, Microbiome, Nutrition and Health Research Unit, Spanish National Research Council, IATA-CSIC, 46980, Paterna-Valencia, Spain.
:
Institute of Agrochemistry and Food Technology, Microbiome, Nutrition and Health Research Unit, Spanish National Research Council, IATA-CSIC, 46980, Paterna-Valencia, Spain.
Principe Felipe Research Center (CIPF), Host-Microbe Interactions in Metabolic Health Laboratory, 46012, Valencia, Spain.
gold, Green Published
|