Toll-like receptors 2 and 4 differentially regulate the self-renewal and differentiation of spinal cord neural precursor cells.
Por:
Sanchez-Petidier M, Guerri C and Moreno-Manzano V
Publicada:
21 mar 2022
Resumen:
Toll-like receptors (TLRs) represent critical effectors in the host defense response against various pathogens; however, their known function during development has also highlighted a potential role in cell fate determination and neural differentiation. While glial cells and neural precursor cells (NPCs) of the spinal cord express both TLR2 and TLR4, their influence on self-renewal and cell differentiation remains incompletely described.
Filiaciones:
:
Neuronal and Tissue Regeneration Laboratory, Prince Felipe Research Institute, Valencia, Spain
Neuropathology Laboratory, Prince Felipe Research Institute, Valencia, Spain
:
Neuropathology Laboratory, Prince Felipe Research Institute, Valencia, Spain.
:
Neuronal and Tissue Regeneration Laboratory, Prince Felipe Research Institute, Valencia, Spain.
Green Submitted, gold, Green Published
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