Sucrose-Responsive Intercommunicated Janus Nanoparticles Network.
Por:
Jimenez-Falcao S, Torres D, Martínez-Ruiz P, Vilela D, Martínez-Máñez R and Villalonga R
Publicada:
24 sep 2021
Resumen:
Inspired by biological systems, the development of artificial nanoscale materials that communicate over a short distance is still at its early stages. This work shows a new example of a cooperating system with intercommunicated devices at the nanoscale. The system is based on the new sucrose-responsive Janus gold-mesoporous silica (Janus Au-MS) nanoparticles network with two enzyme-powered nanodevices. These nanodevices involve two enzymatic processes based on invertase and glucose oxidase, which are anchored on the Au surfaces of different Janus Au-MS nanoparticles, and N-acetyl-L-cysteine and [Ru(bpy) 3 ] 2+ loaded as chemical messengers, respectively. Sucrose acts as the INPUT, triggering the sequential delivery of two different cargoes through the enzymatic control. Nanoscale communication using abiotic nanodevices is a developing potential research field and may prompt several applications in different disciplines, such as nanomedicine.
Filiaciones:
Jimenez-Falcao S:
Nanosensor & Nanomachines Group, Department of Analytical Chemistry, Faculty of Chemistry, Complutense University of Madrid, 28040 Madrid, Spain
Torres D:
Nanosensor & Nanomachines Group, Department of Analytical Chemistry, Faculty of Chemistry, Complutense University of Madrid, 28040 Madrid, Spain
Martínez-Ruiz P:
Nanosensor & Nanomachines Group, Department of Analytical Chemistry, Faculty of Chemistry, Complutense University of Madrid, 28040 Madrid, Spain
Vilela D:
Nanosensor & Nanomachines Group, Department of Analytical Chemistry, Faculty of Chemistry, Complutense University of Madrid, 28040 Madrid, Spain
:
Instituto Interuniversitario de Investigación de Reconocimiento Molecular y Desarrollo Tecnológico (IDM), Universitat Politècnica de València, Universitat de València, Camino de Vera s/n, 46022 Valencia, Spain
Research Mix Unit of Disease Mechanisms and Nanomedicine UPV-CIPF, Universitat Politècnica de València, Centro de Investigación Príncipe Felipe, Eduardo Primo Yúfera, 3, 46012 Valencia, Spain
Networking Biomedical Research Centre in Bioengineering, Biomaterials and Nanomedicine, (CIBER-BBN), Av. Monforte de Lemos 3-5, Pabellón 11, Planta 0, 28029 Madrid, Spain
Villalonga R:
Nanosensor & Nanomachines Group, Department of Analytical Chemistry, Faculty of Chemistry, Complutense University of Madrid, 28040 Madrid, Spain
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