Human pre-implantation embryo development
Por:
K. NIAKAN, J. HAN, R. PEDERSEN, C. SIMON and R. PERA
Publicada:
1 mar 2012
Resumen:
Understanding human pre-implantation development has important implications for assisted reproductive technology (ART) and for human embryonic stem cell (hESC)-based therapies. Owing to limited resources, the cellular and molecular mechanisms governing this early stage of human development are poorly understood. Nonetheless, recent advances in non-invasive imaging techniques and molecular and genomic technologies have helped to increase our understanding of this fascinating stage of human development. Here, we summarize what is currently known about human pre-implantation embryo development and highlight how further studies of human pre-implantation embryos can be used to improve ART and to fully harness the potential of hESCs for therapeutic goals.
Filiaciones:
K. NIAKAN:
Univ Cambridge, Dept Physiol Dev & Neurosci, Cambridge CB2 3EG, England
Univ Cambridge, Anne McLaren Lab Regenerat Med, Cambridge CB2 0SZ, England
Univ Cambridge, Ctr Trophoblast Res, Cambridge CB2 0SZ, England
J. HAN:
Stanford Univ, Sch Med, Dept Obstet & Gynecol, Inst Stem Cell Biol & Regenerat Med, Stanford, CA 94305 USA
R. PEDERSEN:
Univ Cambridge, Anne McLaren Lab Regenerat Med, Cambridge CB2 0SZ, England
Univ Cambridge, Ctr Trophoblast Res, Cambridge CB2 0SZ, England
Univ Cambridge, Dept Surg, Cambridge CB2 0QQ, England
:
Univ Valencia, Ctr Invest Principe Felipe, Valencia 46015, Spain
Univ Valencia, IVI, Valencia 46015, Spain
R. PERA:
Stanford Univ, Sch Med, Dept Obstet & Gynecol, Inst Stem Cell Biol & Regenerat Med, Stanford, CA 94305 USA
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